Journal of Shoulder and Elbow Surgery
Volume 16, Issue 5, Supplement , Pages S179-S183 , September 2007

Use of small intestine submucosa in a rat model of acute and chronic rotator cuff tear

References 

  1. Badylak S, Arnoczky S, Plouhar P, Haut R, Mendenhall V, Clarke R, et al. Naturally occurring extracellular matrix as a scaffold for musculoskeletal repair. Clin Orthop Relat Res. 1999;(Suppl):S333–S343
  2. Badylak SF. Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transpl Immunol. 2004;12:367–377
  3. Badylak SF, Tullius R, Kokini K, Shelbourne KD, Klootwyk T, Voytik SL, et al. The use of xenogeneic small intestinal submucosa as a biomaterial for Achilles tendon repair in a dog model. J Biomed Mater Res. 1995;29:977–985
  4. Dejardin LM, Arnoczky SP, Ewers BJ, Haut RC, Clarke RB. Tissue-engineered rotator cuff tendon using porcine small intestine submucosa (Histologic and mechanical evaluation in dogs). Am J Sports Med. 2001;29:175–184
  5. Derwin K, Androjna C, Spencer E, Safran O, Bauer TW, Hunt T, et al. Porcine small intestine submucosa as a flexor tendon graft. Clin Orthop Relat Res. 2004;245–252
  6. Derwin KA, Soslowsky LJ, Green WD, Elder SH. A new optical system for the determination of deformations and strains: calibration characteristics and experimental results. J Biomech. 1994;27:1277–1285
  7. Gimbel JA, Van Kleunen JP, Lake SP, Williams GR, Soslowsky LJ. The role of repair tension on tendon to bone healing in an animal model of chronic rotator cuff tears. J Biomech. 2007;40:561–568
  8. Gimbel JA, Van Kleunen JP, Mehta S, Perry SM, Williams GR, Soslowsky LJ. Supraspinatus tendon organizational and mechanical properties in a chronic rotator cuff tear animal model. J Biomech. 2004;37:739–749
  9. Gomoll AH, Katz JN, Warner JJ, Millett PJ. Rotator cuff disorders: recognition and management among patients with shoulder pain. Arthritis Rheum. 2004;50:3751–3761
  10. Liang R, Woo SL, Takakura Y, Moon DK, Jia F, Abramowitch SD. Long-term effects of porcine small intestine submucosa on the healing of medial collateral ligament: a functional tissue engineering study. J Orthop Res. 2006;24:811–819
  11. Musahl V, Abramowitch SD, Gilbert TW, Tsuda E, Wang JH, Badylak SF, et al. The use of porcine small intestinal submucosa to enhance the healing of the medial collateral ligament—a functional tissue engineering study in rabbits. J Orthop Res. 2004;22:214–220
  12. Schlegel TF, Hawkins RJ, Lewis CW, Motta T, Turner AS. The effects of augmentation with swine small intestine submucosa on tendon healing under tension: histologic and mechanical evaluations in sheep. Am J Sports Med. 2006;34:275–280
  13. Soslowsky LJ, An CH, Johnston SP, Carpenter JE. Geometric and mechanical properties of the coracoacromial ligament and their relationship to rotator cuff disease. Clin Orthop Relat Res. 1994;10–17
  14. Soslowsky LJ, Thomopoulos S, Tun S, Flanagan CL, Keefer CC, Mastaw J, et al. Neer Award 1999 (Overuse activity injures the supraspinatus tendon in an animal model: a histologic and biomechanical study). J Shoulder Elbow Surg. 2000;9:79–84
  15. Thomopoulos S, Hattersley G, Rosen V, Mertens M, Galatz L, Williams GR, et al. The localized expression of extracellular matrix components in healing tendon insertion sites: an in situ hybridization study. J Orthop Res. 2002;20:454–463
  16. Thomopoulos S, Williams GR, Gimbel JA, Favata M, Soslowsky LJ. Variation of biomechanical, structural, and compositional properties along the tendon to bone insertion site. J Orthop Res. 2003;21:413–419
  17. Woo SL, Takakura Y, Liang R, Jia F, Moon DK. Treatment with bioscaffold enhances the fibril morphology and the collagen composition of healing medial collateral ligament in rabbits. Tissue Eng. 2006;12:159–166
  18. Zalavras CG, Gardocki R, Huang E, Stevanovic M, Hedman T, Tibone J. Reconstruction of large rotator cuff tendon defects with porcine small intestinal submucosa in an animal model. J Shoulder Elbow Surg. 2006;15:224–231
  19. Zheng MH, Chen J, Kirilak Y, Willers C, Xu J, Wood D. Porcine small intestine submucosa (SIS) is not an acellular collagenous matrix and contains porcine DNA: possible implications in human implantation. J Biomed Mater Res B Appl Biomater. 2005;73:61–67

 This study was supported by DePuy Biologics, the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases, and a Clinician-Scientist Award from the Orthopaedic Research and Educational Foundation.

PII: S1058-2746(07)00217-0

doi: 10.1016/j.jse.2007.03.009

Journal of Shoulder and Elbow Surgery
Volume 16, Issue 5, Supplement , Pages S179-S183 , September 2007