Journal of Shoulder and Elbow Surgery
Volume 16, Issue 5, Supplement , Pages S158-S163 , September 2007

Experiences with sheep as an animal model for shoulder surgery: Strengths and shortcomings

  • A. Simon Turner, BVSc, MS, Dipl ACVS

      Affiliations

    • Corresponding Author InformationReprint requests: A. Simon Turner, BVSc, MS, Dipl ACVS, Professor, Department of Clinical Sciences, Veterinary Medical Center, Colorado State University, Ft. Collins, CO 80523.

References 

  1. Coleman SH, Fealy S, Ehteshami JR, Macgillivary JD, Altcheck DW, Warren RF, et al. Chronic rotator cuff injury and repair model in sheep. J Bone Joint Surg Am. 2003;85:2391–2402
  2. Cummins CA, Appleyard RC, Strickland S, Haen PS, Chen S, Murrell GA. Rotator cuff repair: an ex-vivo analysis of suture anchor repair techniques on initial load to failure. Arthroscopy. 2005;21:1236–1241
  3. Gerber C, Schneeberger AG, Beck M, Schlegel U. Mechanical strength of repairs of the rotator cuff. J Bone Joint Surg Br. 1994;76:371–380
  4. Gerber C, Meyer DC, Schneeberger AG, Hoppeler H, von Rechenberg B. Effect of tendon release and delayed repair on the structure of the muscles of the rotator cuff: an experimental study in sheep. J Bone Joint Surg Am. 2004;86:1973–1982
  5. Gerber C, Schneeberger AG, Perren SM, Nyffeler RW. Experimental rotator cuff repair (A preliminary study). J Bone Joint Surg Am. 1999;81:1281–1290
  6. Harrison JA, Wallace D, Van Sickle D, Martin T, Sonnabend DH, Walsh WR. A novel suture anchor of high-density collagen compared with a metallic anchor (Results of a 12-week study in sheep). Am J Sports Med. 2000;28:883–887
  7. Kelly BT, Turner AS, Bansal M. In-vivo healing response after capsular plication in an ovine shoulder model. In: Proceedings of the 50th Annual Meeting of the Orthopaedic Research Society. San Francisco, CA. 2004;p. 209
  8. Lewis CW, Schlegel TF, Hawkins RJ, James SP, Turner AS. Comparison of tunnel suture and suture anchor methods as a function of time in a sheep model. Biomed Sci Instrum. 1999;35:403–408
  9. Lewis CW, Schlegel TF, Hawkins RJ, James SP, Turner AS. The effect of immobilization on rotator cuff healing using modified Mason-Allen: a biomechanical study in sheep. Biomed Sci Instrum. 2001;37:263–268
  10. Ma CB, MacGillivray JD, Clabeaux J, Lee S, Otis JC. Biomechanical evaluation of arthroscopic rotator cuff stitches. J Bone Joint Surg Am. 2004;86:1211–1216
  11. Meyer DC, Hoppeler H, von Rechenberg B, Gerber C. A pathomechanical concept explains muscle loss and fatty muscular changes following surgical tendon release. J Orthop Res. 2004;22:1004–1007
  12. Motta T, Tokish JM, Schlegel TF, Hawkins RJ, Trumble TN, MacLeay JM, et al. Enhancement of infraspinatus tendon healing with pulsed low intensity ultrasound in an ovine model: biomechanical evaluation. [abstract] In: Proceedings of the 51st Annual Meeting of the Orthopaedic Research Society. Washington, DC. 2005;p. 725
  13. Motta T, Tokish JM, Schlegel TF, Hawkins RJ, Trumble TN, MacLeay JM, et al. Histological response to low intensity pulsed ultrasound on rotator cuff repair healing in an ovine model. [abstract] In: Proceedings of the 51st Annual Meeting of the Orthopaedic Research Society. Washington, DC. 2005;p. 632
  14. Obrzut SL, Hecht P, Hayashi K, Fanton GS, Thabit G, Markel MD. The effect of radiofrequency energy on the length and temperature properties of the glenohumeral joint capsule. Arthroscopy. 1998;14:395–400
  15. Rodeo S, Atkinson B, Kim HJ, Campbell D, Turner AS, Potter H. Augmentation of rotator cuff tendon-to-bone repair using a mixture of bone morphogenetic proteins in an ovine model. [abstract] In: Proceedings of the 48th Annual Meeting of the Orthopaedic Research Society. Dallas, TX. 2002;p. 145
  16. Schlegel TF, Hawkins RJ, Lewis CW, Motta T, Turner AS. The effects of augmentation with swine small intestine submucosa on tendon healing under tension: histologic and mechanical evaluations in sheep. Am J Sports Med. 2006;34:275–280
  17. St Pierre P, Olson EJ, Elliott JJ, O’Hair KC, McKinney LA, Ryan J. Tendon-healing to cortical bone compared with healing to a cancellous trough a biomechanical and histological evaluation in goats. J Bone Joint Surg Am. 1995;77:1858–1866
  18. Turner AS. Research in orthopaedic surgery. In:  Souba W,  Wilmore D editor. Surgical research. San Diego, CA: Academic Press; 2001;p. 80–8180-64

PII: S1058-2746(07)00189-9

doi: 10.1016/j.jse.2007.03.002

Journal of Shoulder and Elbow Surgery
Volume 16, Issue 5, Supplement , Pages S158-S163 , September 2007

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